Today, FTSE 100 index in London saw some change, when it resumed after four days of Christmas celebration.

This change made the Hips and knees maker Smith & Nephew to witness their biggest fall on the blue chip index as the investors felt fear at a recent warning from US regulators.

The U. K. medical device manufacturer Smith & Nephew on Thursday reported its second-quarter net profit increase by 16% as improved margins and superior sales of its knothole surgery and lesion care products offset flat sales of its substitution hips in the U. S.

On Friday, the British medical devices company Smith & Nephew Plc., reported a 73% rise in third-quarter net profit and shared the anticipation that the market for replacement hips and knees is stabilizing.