Fourteen common genetic variants increasing risk of sudden cardiac death identified
Dr. Christopher Newton-Cheh

Recent study showed link between fourteen common genetic variants with the increased risk of sudden cardiac death. Research team led by Dr. Christopher Newton-Cheh, of the Massachusetts General Hospital (MGH) Center for Human Genetic Research and Cardiovascular Research Center analyzed genetic data from more than 13,000 people.

Another study also confirmed the association between these 12 variants with the increased risk. QT interval is basically the time from the beginning of electrical activation of the heart to the end of electrical relaxation .QT interval measured on electrocardiograms (EKGs) is used to assess patients' heart health. People with prolonged QT intervals have a higher risk of cardiac death.

Researchers said that the study could help prevent heart arrhythmia and prevent sudden cardiac death by limiting the use of medications that affect QT interval in people with these 14 gene variants, which are located in 10 different gene regions.

Dr. Christopher Newton-Cheh said: "From studies of families with congenital long-QT syndrome, we know that rare mutations with strong effects on ion channel function lead to QT prolongation and sudden death. But the common genetic basis for QT prolongation has been very difficult to establish."

Newton-Cheh emphasized that it's "premature to advocate screening gene variants for risk assessment, but someday it may be possible to identify individuals who are particularly high risk and should avoid" medications that can cause QT prolongation.

Latest News

Father Shoots Girl’s Laptop, Posts Video on Youtube
Apple Begins Inspection
Researchers Blame Technological Advancements For Kids’ Poor Sleeping Pattern
The Google Motorola Deal Approved By US and EU
Replace Sugary Drinks with Water to Lose Weight
NASA Scientists Develop New Space Testbed
Scientists Expecting Life at Icy Dark and Cold Regions
Mysteries Behind Milky Way Galaxy To Be Unveiled
Scientific Equation behind the Shape of Ponytail Unveiled
Cooma People Encouraged To Donate Blood
Knox Receives Less Dental Care Funding
Massive Fight in Sydney Club